Horizontal Gene Transfer Database

 

Proposed horizontally transferred genes for Streptococcus pyogenes MGAS8232 (See the Abbreviations used):
Coordinates  Strand Length PID Gene name Synonym FunctionCode COG GCRegion HGT SimGC SimMah Dev.AA Function
8869..9141 + 270 19745207 - spyM18_0008 - - - H 2 2 conserved hypothetical protein
9128..9499 + 369 19745208 divIC spyM18_0009 - - - H 2 1 +K 4.2 putative cell division protein
9634..10920 + 1284 19745209 - spyM18_0011 - - - H 2 0 hypothetical protein
10917..12203 + 1284 19745210 mesJ spyM18_0012 - - - H 2 0 putative cell-cycle protein
12208..12750 + 540 19745211 hpt spyM18_0013 - - - H 2 0 putative hypoxanthine-guanine phosphoribosyltransferase
15077..16468 + 1389 19745213 - spyM18_0015 - - - H 1 0 putative amino acid permease
42197..43219 + 1020 19745222 purM spyM18_0028 - - + H 1 0 putative phosphoribosylformylglycinamide cyclo-ligase
43387..43941 + 552 19745223 purN spyM18_0029 - - + H 2 0 Phosphoribosylglycinamide formyltransferase
44125..45672 + 1545 19745224 purH spyM18_0030 - - + H 2 0 putative phosphoribosyl carboxyamide aminoimidazole transformylase
47108..48373 + 1263 19745226 purD spyM18_0032 - - + H 2 0 phosphoribosylamine-glycine ligase
48532..49143 + 609 19745227 purE spyM18_0033 - - + H 2 0 putative phosphoribosylaminoimidazole carboxylase I
49094..50203 + 1107 19745228 purK spyM18_0034 - - + H 2 1 phosphoribosylaminoimidazole carboxylase II
120829..121863 + 1032 19745303 - spyM18_0128 - - - H 1 0 +T 3.2 hypothetical protein
121864..122604 + 738 19745304 - spyM18_0129 - - - H 1 0 hypothetical protein
122621..123208 + 585 19745305 - spyM18_0130 - - - H 0 0 hypothetical protein
123368..124573 - 1203 19745306 - spyM18_0131 - - - H 0 0 putative multiple sugar metabolism repressor
124958..127048 + 2088 19745307 prtF2l spyM18_0132 - - - H 0 0 protein F2-like protein
127314..127979 - 663 19745308 - spyM18_0133 - - - H 0 0 +W 4.0 hypothetical protein
175554..176009 + 453 19745350 - spyM18_0185 - - H 1 2 conserved hypothetical protein
180845..181324 + 477 19745357 - spyM18_0196 - - H 1 1 conserved hypothetical protein
217914..218738 + 822 19745392 - spyM18_0243 - - + H 0 0 conserved hypothetical protein
218731..219300 + 567 19745393 - spyM18_0244 - - + H 1 0 +R 3.3 conserved hypothetical protein
219414..220286 + 870 19745394 ksgA spyM18_0246 - - + H 1 0 putative dimethyladenosine transferase
220709..221581 + 870 19745395 - spyM18_0247 - - + H 0 0 conserved hypothetical protein
221591..222253 + 660 19745396 - spyM18_0248 - - + H 0 0 putative ribulose-phosphate 3-epimerase
296536..296886 - 348 19745458 - spyM18_0340 - - H 2 1 putative repressor protein
302301..303113 + 810 19745467 - spyM18_0350 - - H 1 2 putative phage DNA replication protein
328959..329591 + 630 19745502 - spyM18_0388 - - H 1 1 hypothetical phage protein
370763..371086 + 321 19745553 - spyM18_0455 - - H 1 2 conserved hypothetical protein
382949..384946 + 1995 19745562 metS spyM18_0468 - - + H 1 0 putative methionyl-tRNA synthetase
385440..386453 + 1011 19745563 nrdF spyM18_0470 - - + H 1 0 putative ribonucleotide reductase 2
386457..386945 + 486 19745564 nrdI spyM18_0471 - - + H 0 2 +H 4.0 putative ribonucleotide reductase
386912..389092 + 2178 19745565 - spyM18_0472 - - + H 1 0 ribonucleoside-diphosphate reductase, large chain
389324..390049 - 723 19745566 - spyM18_0476 - - + H 2 2 +C 3.8 conserved hypothetical protein
391272..391523 + 249 19745568 - spyM18_0479 - - + H 2 2 +V 4.3 hypothetical protein
392440..392715 + 273 19745570 - spyM18_0482 - - + H 0 2 +W 3.0 hypothetical protein
419377..419853 + 474 19745600 - spyM18_0518 - - H 1 1 conserved hypothetical protein
437734..438180 + 444 19745612 - spyM18_0549 - - H 1 2 hypothetical protein
483798..484724 + 924 19745656 aroD spyM18_0600 - - - H 2 0 putative shikimate 5-dehydrogenase
484721..485557 + 834 19745657 - spyM18_0601 - - - H 2 0 +I 3.1 hypothetical protein
485559..486293 + 732 19745658 - spyM18_0602 - - - H 1 0 conserved hypothetical protein
486286..487272 + 984 19745659 - spyM18_0603 - - - H 2 0 hypothetical protein
487282..488481 + 1197 19745660 - spyM18_0604 - - - H 2 0 putative S-adenosylmethionine synthetase
488474..489433 + 957 19745661 - spyM18_0605 - - - H 2 0 hypothetical protein
489488..490477 + 987 19745662 - spyM18_0606 - - - H 2 0 conserved hypothetical protein
490880..491032 + 150 19745663 - spyM18_0607 - - - H 2 2 hypothetical protein
491169..492326 + 1155 19745664 - spyM18_0608 - - - H 2 0 putative nucleotide sugar dehydrogenase
492411..493619 + 1206 19745665 - spyM18_0609 - - - H 2 0 putative efflux protein
493721..493930 - 207 19745666 - spyM18_0610 - - - H 2 2 +I 3.8 conserved hypothetical protein
498430..498762 + 330 19745675 - spyM18_0621 - - H 1 2 hypothetical protein
499167..499505 + 336 19745676 - spyM18_0622 - - - H 2 2 hypothetical protein
499529..500206 + 675 19745677 - spyM18_0624 - - - H 1 0 hypothetical protein
500331..500942 + 609 19745678 - spyM18_0626 - - - H 2 0 N-terminal fragment of SPy0560
501536..502555 + 1017 19745679 - spyM18_0630 - - - H 1 0 putative immunity protein
502568..502768 + 198 19745680 - spyM18_0631 - - - H 2 2 +H 3.4 hypothetical protein
502888..503373 + 483 19745681 - spyM18_0632 - - - H 2 1 +I 3.1 hypothetical protein
503370..503786 + 414 19745682 - spyM18_0633 - - - H 2 0 hypothetical protein
504159..504962 - 801 19745683 tnpA spyM18_0634 - - - H 1 0 transposase TnpA fragment
578093..579508 - 1413 19745752 int spyM18_0716 - - - H 1 0 putative integrase; bacteriophage 370.1
579631..579936 - 303 19745753 - spyM18_0717 - - - H 1 2 +C 5.3 hypothetical protein
579946..580710 - 762 19745754 - spyM18_0718 - - - H 0 0 putative repressor protein
581327..581968 - 639 19745756 - spyM18_0721 - - - H 1 0 hypothetical protein
582020..582208 + 186 19745757 - spyM18_0722 - - - H 2 2 putative cro protein
583428..583565 + 135 19745759 - spyM18_0724 - - - H 1 2 +C 4.7 hypothetical phage protein
686820..687581 + 759 19745871 - spyM18_0848 - - - H 0 0 putative ABC-transporter (permease protein)
687581..688786 + 1203 19745872 - spyM18_0849 - - - H 0 0 ABC transporter (ATP-binding protein)
688811..689818 + 1005 19745873 - spyM18_0852 - - - H 1 0 putative glycosyltransferase
689815..691560 + 1743 19745874 - spyM18_0853 - - - H 2 0 conserved hypothetical protein
691557..694031 + 2472 19745875 - spyM18_0855 - - - H 1 0 conserved hypothetical protein
694210..694905 + 693 19745876 - spyM18_0856 - - - H 0 0 putative glycosyl transferase
694907..695248 + 339 19745877 - spyM18_0858 - - - H 2 2 +FL 3.4 3.3 hypothetical protein
695241..696527 + 1284 19745878 - spyM18_0859 - - - H 2 0 conserved hypothetical protein
696508..698004 + 1494 19745879 - spyM18_0860 - - - H 2 0 conserved hypothetical protein
699362..699850 + 486 19745881 - spyM18_0862 - - - H 1 0 putative pore-forming peptide
699837..700034 - 195 19745882 - spyM18_0863 - - - H 1 2 +CS 8.7 5.4 putative ferredoxin
700083..700559 + 474 19745883 - spyM18_0864 - - - H 1 0 +T 4.4 hypothetical protein
801431..801733 - 300 19745978 - spyM18_0972 - - H 1 2 hypothetical protein
894560..894673 + 111 19746065 - spyM18_1077 - - - H 2 2 +KST 4.7 5.0 -3.4 hypothetical protein
894673..895821 + 1146 19746066 - spyM18_1078 - - - H 1 0 hypothetical protein
895870..896550 + 678 19746067 radC spyM18_1079 - - - H 1 0 putative DNA repair protein
898153..898500 - 345 19746070 - spyM18_1082 - - - H 2 0 hypothetical protein
964989..966212 - 1221 19746137 - spyM18_1156 - - - H 0 0 putative antimicrobial resistance factor
968251..968415 + 162 19746139 - spyM18_1158 - - - H 1 2 +PT 6.0 4.2 hypothetical protein
968256..968813 - 555 19746140 - spyM18_1159 - - - H 1 0 hypothetical protein
968791..969657 - 864 19746141 pdxK spyM18_1160 - - - H 0 0 putative pyridoxal kinase
969747..971015 + 1266 19746142 - spyM18_1161 - - - H 1 0 conserved hypothetical protein
971160..971273 + 111 19746143 - spyM18_1162 - - - H 2 2 +KT 6.8 -3.4 hypothetical protein
972101..973678 - 1575 19746145 cls spyM18_1164 - - - H 0 0 putative cardiolipin synthetase
986826..987890 - 1062 19746159 - spyM18_1178 - - - H 0 0 putative sugar ABC transporter (permease protein)
990700..991089 - 387 19746162 cdd spyM18_1181 - - - H 1 2 +C 4.0 putative cytidine deaminase
991598..992191 - 591 19746163 - spyM18_1182 - - - H 0 0 conserved hypothetical protein
992459..993379 + 918 19746164 coaA spyM18_1183 - - - H 1 0 putative pantothenate kinase
993806..995116 - 1308 19746166 - spyM18_1186 - - - H 2 0 putative histidine kinase protein
995109..995783 - 672 19746167 - spyM18_1187 - - - H 1 0 putative response regulator
1006381..1006785 - 402 19746178 - spyM18_1198 - - H 1 1 conserved hypothetical protein
1038487..1039185 + 696 19746209 - spyM18_1234 - - - H 0 0 putative ABC transporter
1039195..1039980 + 783 19746210 - spyM18_1235 - - - H 1 0 +F 3.4 hypothetical protein
1040107..1040721 - 612 19746211 - spyM18_1236 - - - H 1 0 +I 3.2 hypothetical protein
1041616..1042404 - 786 19746213 - spyM18_1238 - - - H 2 0 putative exotoxin precursor (SpeL)
1042686..1043399 - 711 19746214 - spyM18_1239 - - - H 2 0 putative exotoxin precursor (SpeM)
1043703..1044569 - 864 19746215 - spyM18_1240 - - - H 1 0 hypothetical phage protein
1045221..1045706 - 483 19746217 - spyM18_1242 - - H 1 2 conserved hypothetical phage protein
1239632..1240150 + 516 19746442 - spyM18_1505 - - - H 1 0 +K 3.1 hypothetical phage protein
1240274..1241416 + 1140 19746443 int spyM18_1506 - - - H 0 0 putative integrase
1241539..1241784 + 243 19746444 - spyM18_1508 - - - H 1 2 +ACS 4.4 3.7 4.3 hypothetical protein
1241879..1242466 - 585 19746445 - spyM18_1509 - - - H 1 0 conserved hypothetical protein
1242444..1243304 - 858 19746446 - spyM18_1510 - - - H 1 0 conserved hypothetical protein
1243279..1244118 - 837 19746447 - spyM18_1511 - - - H 0 0 conserved hypothetical protein
1244346..1245293 - 945 19746448 - spyM18_1512 - - - H 0 0 hypothetical protein
1260466..1260768 + 300 19746463 - spyM18_1529 - - H 1 1 hypothetical protein
1298799..1299539 - 738 19746500 - spyM18_1570 - - H 1 1 putative two-component response regulator
1330442..1332136 - 1692 19746528 hyl spyM18_1606 - - + H 0 0 putative hyaluronidase
1332187..1333227 - 1038 19746529 - spyM18_1609 - - + H 0 0 putative transcription regulator
1333333..1334646 + 1311 19746530 - spyM18_1610 - - + H 0 0 conserved hypothetical protein
1334661..1337366 + 2703 19746531 - spyM18_1611 - - + H 0 0 conserved hypothetical protein
1378597..1378923 - 324 19746567 - spyM18_1658 - - H 1 2 conserved hypothetical protein
1646956..1647561 - 603 19746829 - spyM18_1978 - - - H 2 0 putative response regulator of salavaricin regulon
1647542..1649104 - 1560 19746830 - spyM18_1979 - - - H 2 0 putative SalK homologue
1649144..1651051 - 1905 19746831 - spyM18_1980 - - - H 2 0 putative ABC transporter (permease)
1651053..1651790 - 735 19746832 - spyM18_1981 - - - H 1 0 putative salivaricin A ABC transporter
1651787..1654090 - 2301 19746833 - spyM18_1982 - - - H 1 0 putative salivaricin A modification enzyme
1654174..1654329 - 153 19746834 - spyM18_1983 - - - H 1 2 +C 6.5 lantibiotic precursor
1695282..1698779 - 3495 19746878 - spyM18_2038 - - + H 0 0 putative pullulanase
1698977..1700590 - 1611 19746879 - spyM18_2039 - - + H 1 0 +W 3.1 putative dextran glucosidase
1700719..1701852 - 1131 19746880 - spyM18_2040 - - + H 0 0 multiple sugar-binding ABC transport system (ATP-binding protein)
1702150..1702998 - 846 19746881 - spyM18_2041 - - + H 1 0 +Q 3.1 leucine-rich protein
1704758..1705201 - 441 19746883 - spyM18_2044 - - + H 0 0 conserved hypothetical protein
1705216..1707435 - 2217 19746884 - spyM18_2045 - - + H 1 0 (p)ppGpp synthetase
1711010..1711468 + 456 19746887 nrdI spyM18_2048 - - + H 1 2 ribonucleotide reductase-like protein
1711771..1712592 - 819 19746888 - spyM18_2049 - - + H 1 0 hypothetical protein
1712675..1714861 - 2184 19746889 ptsG spyM18_2050 - - + H 1 0 putative PTS system, enzyme II, A component
1715217..1715966 - 747 19746890 - spyM18_2051 - - + H 1 0 conserved hypothetical protein
1715966..1716919 - 951 19746891 prmA spyM18_2052 - - + H 1 0 putative methyltransferase
1716990..1717460 - 468 19746892 - spyM18_2053 - - + H 0 0 hypothetical protein
1717633..1719606 + 1971 19746893 - spyM18_2055 - - + H 2 0 putative amidase
1719791..1721548 + 1755 19746894 - spyM18_2056 - - + H 1 0 putative para-aminobenzoate synthetase
1721581..1722147 + 564 19746895 - spyM18_2057 - - + H 1 0 anthranilate synthase component II
1722180..1723448 + 1266 19746896 - spyM18_2058 - - + H 0 0 conserved hypothetical protein
1786093..1787625 + 1530 19746953 - spyM18_2138 - - + H 1 0 putative NADH oxidase/alkyl hydroperoxidase reductase
1789239..1791269 + 2028 19746955 hutU spyM18_2141 - - + H 1 0 putative urocanate hydratase
1791357..1792256 + 897 19746956 - spyM18_2142 - - + H 1 0 putative formiminotransferase cyclodeaminase
1792267..1792893 + 624 19746957 - spyM18_2143 - - + H 0 0 putative serine cycle enzyme
1792911..1794584 + 1671 19746958 - spyM18_2144 - - + H 2 0 putative formate-tetrahydrofolate ligase
1794606..1795202 + 594 19746959 - spyM18_2145 - - + H 1 1 hypothetical protein
1796776..1798317 + 1539 19746961 - spyM18_2147 - - + H 1 0 putative histidine ammonia-lyase
1798503..1799489 + 984 19746962 - spyM18_2148 - - + H 1 0 putative formiminoglutamate hydrolase
1799520..1802594 - 3072 19746963 - spyM18_2149 - - + H 1 0 putative regulatory protein
1805005..1806900 - 1893 19746966 pepO spyM18_2153 - - + H 0 0 putative endopeptidase O
1807108..1808736 - 1626 19746967 - spyM18_2154 - - + H 0 0 putative dextran glucosidase
1812031..1812369 - 336 19746970 - spyM18_2160 - - H 1 2 hypothetical protein
1870634..1871176 - 540 19747028 - spyM18_2231 - - - H 0 0 phosphatidylglycerophosphate synthase
1871190..1872215 - 1023 19747029 - spyM18_2232 - - - H 0 0 hypothetical protein
1872265..1873554 - 1287 19747030 - spyM18_2233 - - - H 1 0 hypothetical protein
1873556..1874800 - 1242 19747031 - spyM18_2234 - - - H 2 0 hypothetical protein
1875187..1876446 + 1257 19747032 hasA spyM18_2236 - - - H 1 0 hyaluronate synthase A
1876482..1877690 + 1206 19747033 hasB spyM18_2237 - - - H 2 0 UDP-glucose 6-dehydrogenase
1879094..1879507 + 411 19747035 - spyM18_2241 - - - H 0 0 conserved hypothetical protein

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